This whitepaper describes the development and use of a cost model encompassing capital, labor, materials, consumables, and other costs, which are five key parameters of manufacturing for a variety of vaccine modalities: vaccines which use inactivated and attenuated viruses, protein subunit vaccines, virus-like particles (VLP) vaccines, Viral vector vaccines, and mRNA vaccines.

Manufacturing costs, which reside between the lengthy and highly variable costs of process development and commercialization, are more easily defined and therefore more amenable to being assessed via cost modeling.

The model was developed using BioSolve software (Biopharm Services) and was based on inputs related to the process flow and parameters, cost of materials, and other assumptions.

More insights from this white paper can be found here.