Maximize AAV Vector Production from Suspension HEK293 Cells

by John Sotirakos | January 10, 2024

Adeno-associated viral (AAV) vectors are a cornerstone of gene therapies, used to deliver nucleic acid to target tissues. Production of these vectors using suspension culture offers significant advantages over traditional adherent cell culture approaches which have historically used animal-derived media supplements such as fetal bovine serum.

It is important to have an HEK293 AAV viral vector platform that is optimized for production and scale-up of suspension cultures of HEK293 cells for AAV manufacturing. The right chemically defined animal component-free cell culture media is a possible solution that has been formulated to maximize cell growth, vector production, and speed to the clinic while reducing manufacturing risk.

Learn how to optimize suspension HEK293 cell culture production of AAV vectors and improve flexibility across serotypes.

Senior Marketing Communications Manager, Cell & Gene Therapy - BioProcessing

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